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Jan 2, 2026 · In this issue of the JCI, Goala et al. uncovered a mechanistic link between IFN-γ–driven inflammation and disrupted neutrophil homeostasis, revealing that cytokine release syndrome (CRS) …
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Genetic and environmental influences in autism: guiding the future of tailored early detection and intervention
JCI - Volume 135, Issue 1
Jan 2, 2025 · In this issue of the JCI, Derakhshan et al. elucidate the heterogeneity of MCs in nasal polyposis and identify a transcriptional signature of TGF-β target genes expressed by the …
JCI - The gut microbiome and cancer response to immune checkpoint ...
Feb 3, 2025 · The field of the microbiome and immunotherapy has skyrocketed since 2015 when two studies demonstrated a fascinating phenomenon in mice: certain gut bacteria could enhance the …
JCI - Loss of Cpt1a results in elevated glucose-fueled mitochondrial ...
Jan 9, 2025 · J Clin Invest. 2010;120 (1):142–156. View this article via: JCI CrossRef PubMed Google Scholar Ricciardi MR, et al. Targeting the leukemia cell metabolism by the CPT1a inhibition: …
JCI Insight - Frequency of dengue virus–specific T cells is related to ...
Feb 24, 2025 · The frequency of PD-1 expression among AIM + CD4 + T cells did not show an accumulation or increase in children with a higher number of dengue cases or a significant difference …