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  1. Physiology, NMDA Receptor - StatPearls - NCBI Bookshelf

    Dec 11, 2022 · The N-methyl-D-aspartate (NMDA) receptor is a glutamate receptor, the human brain's primary excitatory neurotransmitter. It plays an integral role in synaptic plasticity, a …

  2. NMDA receptor - Wikipedia

    The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca 2+ ion channel found in neurons. [3][4] The NMDA …

  3. What are NMDA Receptors? - News-Medical.net

    Nov 24, 2024 · N-methyl D-aspartate (NMDA) receptors are ligand-gated cation channels activated by an excitatory neurotransmitter, glutamate.

  4. New advances in small molecule drugs targeting NMDA receptors

    Nov 4, 2025 · N -methyl- D -aspartate (NMDA) receptors are glutamate-gated ion channels that are ubiquitously expressed throughout the central nervous system (CNS) and serve as crucial …

  5. NMDA receptor functions in health and disease: Old actor, new ...

    Dupuis et al. discuss recent advances in our understanding of the glutamatergic NMDA receptor, focusing mainly on the dynamics and nanoscale organization of membrane NMDA receptors …

  6. NMDA Receptor - an overview | ScienceDirect Topics

    NMDA receptors (NMDARs) are defined as prominent ligand-gated ion channels that play a crucial role in excitatory synaptic transmission in the central nervous system, and are essential …

  7. NMDA receptors in the central nervous system - PMC

    Here, we will review the relationship between NMDA receptor structure and function, the diversity and significance of NMDA receptor subtypes in the CNS, as well as principles and rules by …

  8. Mechanisms of NMDA receptor regulation - ScienceDirect

    Dec 1, 2023 · N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels widely expressed in the central nervous system that play key role in brain development and …

  9. NMDA Receptors in Neurodevelopmental Disorders: …

    NMDA receptors (NMDARs) are cation-specific ligand-gated ion channels that mediate glutamatergic synaptic transmission throughout the CNS. The NMDARs are localized on …

  10. What are NMDA receptor agonists and how do they work?

    Jun 21, 2024 · NMDA receptors are ionotropic receptors, meaning they function as ion channels that allow for the flow of ions across the cell membrane when activated. These receptors are …