This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

For decades, biology has relied on one central assumption: the genetic code is precise. DNA is transcribed into RNA, RNA is ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

Researchers uncovered a microbe that treats one stop codon as both a termination signal and an amino-acid instruction, revealing surprising genetic flexibility that may inspire new ways to influence ...

Scientists in the UK have rewritten one of life’s oldest operating systems. They have built a bacterium that functions with a stripped-down genetic code, eliminating seven of the 64 instructions used ...

Alltrna, the preclinical Flagship Pioneering-backed biotech trying to turn transfer RNA (tRNA) into drugs, is slimming down as it works toward the clinic. The Massachusetts-based outfit has laid off ...

test sequence_of_two_different_protein_codons_translates_into_proteins ... ok test sequence_of_two_protein_codons_translates_into_proteins ... ok test serine_rna ...

Yale scientists have reprogrammed the genetic code of an organism, creating a novel genomically recoded organism (GRO) with only one stop codon, enabling the production of synthetic proteins with new ...