AZoLifeSciences on MSN
Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...
Indian Defence Review on MSN
This Microbe Just Broke a Rule of Biology Scientists Thought Was Unbreakable
Scientists have identified a microbe capable of interpreting a single piece of genetic code in two completely different ways.
This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
Rare diseases, defined by FDA as “a disease or condition that affects less than 200,000 people in the United States” (1), may ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends ...
This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
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