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Key protein in the tuberculosis bacterium helps protect itself from foreign DNA

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), ...

How Mycobacterium tuberculosis safeguards itself from foreign DNA

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), ...

Single-cell testing shows which antibiotics actually kill bacteria, not just stop growth

Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory ...

Noninvasive prenatal screening could prevent permanent hearing loss in newborns

A new study indicates that noninvasive prenatal screening (NIPS) performed using a low-cost form of whole genome sequencing ...
eLife

Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...