Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

Targeting SUMOylation in glioblastoma opens new avenue for therapeutic interventions and biomarker discovery Glioblastoma, a ...

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich ...

Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in our cells. They now show that this complex also controls the processing of ...

Post-translational modifications (PTMs) represent a pivotal regulatory mechanism in cellular processes, wherein the addition or removal of specific functional groups to amino acid residues dynamically ...

Adding a banana to your berry smoothie might sound healthy, but new research suggests the popular combo could cancel out some of the fruit's benefits. Scientists at the University of California, Davis ...

Scientists at Rice University have engineered living cells to light up like tiny beacons, revealing protein changes in real time. This groundbreaking method could transform the way researchers study ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

DOMEK is a multi-step pipeline which leverages mRNA display-derived next-generation sequencing data to derive kinetic information about substrates of post-translational modification enzymes.

This study provides valuable insights into microtubule remodeling during liver-stage Plasmodium berghei development, demonstrating that deletion of the alpha-tubulin C-terminal tail impairs parasite ...