This article deals with layouts involving one random factor and at least one fixed factor crossed with the random factor, where the sum of the observations on each level of the random factor must ...

Meta-analysis is a commonly used approach to increase the sample size for genome-wide association searches when individual studies are otherwise underpowered. Here, we present a meta-analysis ...

In most GWAS, the participants are assumed to be unrelated and to come from a single population. However, even in carefully designed studies, some degrees of relatedness and population stratification ...