The Escherichia coli enzyme 3-methyladenine DNA glycosylase I (TAG) hydrolyzes the glycosidic bond of 3-methyladenine (3-MeA) in DNA and is found in many bacteria and some higher eukaryotes. TAG shows ...
The structure of TAG, a DNA repair enzyme, reveals how evolutionary changes in the sequence of a conserved scaffold may enrich the mechanistic diversity of the DNA HhH glycosylase superfamily through ...