The human brain contains billions of connected neurons that collectively support different mental functions, including the ...

New research challenges the century-old practice of mapping the brain based on how tissue looks under a microscope. By analyzing electrical signals from thousands of neurons in mice, scientists ...

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no cure and limited treatment options.

Researchers have developed the first activity-based maps of the prefrontal cortex, challenging traditional descriptions of ...

Different neuronal cells have a diverse range of activity patterns, but the cause has remained unclear. In mice, maps of brain-wide inputs to individual neurons that do or do not show activity ...

Why is sleep so important for learning and memory? Neuroscientists from the Csicsvari group at the Institute of Science and Technology Austria (ISTA) provided new insight into this essential function ...

Scientists have developed a computer-based model that may explain how nerve cells become damaged in ALS, and how best to time ...

For more than a century, maps of the brain have been based on how brain tissue looks under the microscope.

Researchers have developed a new type of pipette that can deliver ions to individual neurons without affecting the sensitive extracellular milieu. Controlling the concentration of different ions can ...

Developmental electrophysiological adaptations and heat-sensitive proteins, such as TRPV3, in cortical excitatory neurons help maintain stable activity levels when brain temperature rises by 2–3°C ...

What goes wrong first in the Alzheimer’s disease brain? Scientists led by Marc Aurel Busche of the U.K. Dementia Research Institute at University College London may have an answer. In the May 7 Neuron ...