TRPML1 is a promising target1 for Parkinson’s disease treatments and identifying translational biomarkers will help confirm target engagement ...

A multidisciplinary team has developed a selective compound that inhibits an enzyme tied to inflammation in people at genetic ...

Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...

An illustration shows a molecule nestled inside a large lumpy green mass. According to researchers' predictions, the antiviral candidate, venetoclax (red and purple), could limit SARS-CoV-2's ability ...

Monash University scientists have identified a potential new drug target to alleviate neuroinflammation, which is reported in many neurodegenerative diseases, such as Alzheimer's, Parkinson's and ...

Developing high-quality, safe, and effective drugs is a complex process that requires varied scientific skills and stringent regulatory assessments. Drug development is a process that spans many years ...